Basic Information
ID: ALA3366942
Type: Functional
Description: Antitrypanosomal activity against Trypanosoma cruzi Y luc infected in mouse assessed as inhibition of parasitemia at 50 mg/kg, po bid in 20% Kolliphor administered for 4 consecutive days starting on day 3 of infection measured on day 7 post infection relative to vehicle-treated control
Organism: Trypanosoma cruzi
Strain: Y luc
Activity Charts
Bioactivity
Activity Types for Assay ALA3366942
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 240.31 | 3.21 | 3.21 |
| 496.52 | 5.49 | 5.49 |
| 514.51 | 5.63 | 5.63 |
| 514.51 | 5.63 | 5.63 |
| 546.52 | 6.37 | 6.37 |
| 620.63 | 7.21 | 7.21 |
| 564.51 | 6.51 | 6.51 |
| 564.51 | 6.51 | 6.51 |
| 530.96 | 6.14 | 6.14 |
| 580.64 | 5.15 | 5.15 |
| 528.59 | 3.35 | 3.35 |
| 597.09 | 5.66 | 5.66 |
| 598.63 | 5.29 | 5.29 |
| 598.63 | 5.29 | 5.29 |