Basic Information
ID: ALA3367339
Type: ADME
Description: Therapeutic index, ratio of cytotoxic IC50 for human THP1 cells by MTT assay to IC50 for inhibition of LPS-induced IL6 production in human THP1 cells
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: ADMET(ALA612558)
Document: ALA3351580
Therapeutic index, ratio of cytotoxic IC50 for human THP1 cells by MTT assay to IC50 for inhibition of LPS-induced IL6 production in human THP1 cells: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3367339
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 328.27 | -1.20 | -1.20 |
| 413.42 | -0.36 | -0.36 |
| 440.45 | -1.45 | -1.45 |