Antiinflammatory activity in BALB/c mouse assessed as serum IL6 level at 10 mg/kg, po qd for 5 days followed by LPS challenge 1 hr after last compound...

Basic Information

ID: ALA3367342

Type: Functional

Description: Antiinflammatory activity in BALB/c mouse assessed as serum IL6 level at 10 mg/kg, po qd for 5 days followed by LPS challenge 1 hr after last compound dose on fifth day and measured 4 hrs post LPS challenge by ELISA method (Rvb = 410 +/- 95 pg/mL)

Format: BAO_0000218

Organism: Mus musculus

Strain: BALB/c

Tissue: Serum

Target:  Mus musculus(ALA375)

Document:  ALA3351580

Antiinflammatory activity in BALB/c mouse assessed as serum IL6 level at 10 mg/kg, po qd for 5 days followed by LPS challenge 1 hr after last compound dose on fifth day and measured 4 hrs post LPS challenge by ELISA method (Rvb = 410 +/- 95 pg/mL): 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
328.27-1.20-1.20
413.42-0.36-0.36
440.45-1.45-1.45