Assay Report Card

Basic Information

ID: ALA3367358

Type: Functional

Description: Antiarthritic activity in DBA/1J mouse collagen-induced arthritis model assessed as reduction in TNFalpha level at 3 to 30 mg/kg, po administered once daily for 49 days starting from onset of disease and measured after 3 to 49 days of disease onset by ELISA method

Organism: Mus musculus

Strain: DBA/1J

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
328.27-1.20-1.20
413.42-0.36-0.36
440.45-1.45-1.45