Basic Information
ID: ALA3369326
Type: Binding
Description: Inhibition of FPPS in human SH-SY5Y cells assessed as blocking of tau metabolism by measuring ratio of tau phosphorylation to total tau level at 100 nM after 24 hrs by ELISA (Rvb = 0.012 no-unit)
Organism: Homo sapiens
Cell type: SH-SY5Y
Activity Charts
Bioactivity
Activity Types for Assay ALA3369326
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 283.11 | -0.37 | -0.37 |
| 267.11 | 0.31 | 0.31 |
| 187.13 | 0.80 | 0.80 |
| 269.26 | 2.58 | 2.58 |
| 400.26 | 2.34 | 2.34 |
| 415.30 | 2.72 | 2.72 |
| 457.34 | 2.95 | 2.95 |
| 335.33 | 3.21 | 3.21 |
| 349.35 | 3.26 | 3.26 |
| 334.34 | 3.39 | 3.39 |
| 299.36 | 3.16 | 3.16 |
| 369.77 | 3.87 | 3.87 |
| 445.87 | 5.61 | 5.61 |
| 290.11 | -1.12 | -1.12 |