Assay Report Card

Basic Information

ID: ALA3369541

Type: Binding

Description: Inhibition of SHP2 in human NCI-H1975 cells assessed as reduction in EGF-induced Erk1/2 phosphorylation at 2 uM after 60 mins by immunoblot analysis in presence of SHP2 siRNA relative to control

Organism: Homo sapiens

Cell type: NCI-H1975

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
637.466.166.16