Basic Information
ID: ALA3370374
Type: Binding
Description: Inhibition of SUMO-tagged human TTK (1-275 residues) compound pre-incubated for 15 mins prior ATP addition by MBP-based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3370374
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 273.32 | 1.88 | 1.88 |
| 307.76 | 2.53 | 2.53 |
| 385.40 | 3.82 | 3.82 |
| 349.42 | 3.54 | 3.54 |
| 349.42 | 3.54 | 3.54 |
| 303.34 | 1.89 | 1.89 |
| 303.34 | 1.89 | 1.89 |
| 330.37 | 1.84 | 1.84 |
| 330.37 | 1.84 | 1.84 |
| 398.47 | 3.19 | 3.19 |
| 398.47 | 3.19 | 3.19 |
| 330.37 | 1.24 | 1.24 |
| 379.44 | 3.46 | 3.46 |
| 399.50 | 3.56 | 3.56 |
| 406.47 | 3.06 | 3.06 |
| 412.50 | 3.12 | 3.12 |
| 434.52 | 2.74 | 2.74 |
| 456.55 | 3.13 | 3.13 |
| 407.45 | 3.52 | 3.52 |
| 463.56 | 4.65 | 4.65 |
| 477.59 | 4.67 | 4.67 |
| 443.51 | 2.65 | 2.65 |
| 499.62 | 3.77 | 3.77 |
| 406.47 | 2.81 | 2.81 |
| 412.50 | 2.87 | 2.87 |
| 420.49 | 3.15 | 3.15 |
| 406.47 | 2.81 | 2.81 |
| 420.49 | 3.37 | 3.37 |
| 420.49 | 3.45 | 3.45 |
| 407.46 | 2.45 | 2.45 |
| 407.46 | 2.45 | 2.45 |
| 420.49 | 3.12 | 3.12 |
| 420.49 | 3.37 | 3.37 |
| 462.58 | 4.18 | 4.18 |
| 462.58 | 3.93 | 3.93 |
| 475.57 | 2.89 | 2.89 |
| 432.51 | 3.55 | 3.55 |
| 432.51 | 3.30 | 3.30 |
| 434.52 | 4.01 | 4.01 |
| 448.55 | 4.26 | 4.26 |
| 446.53 | 3.76 | 3.76 |
| 452.56 | 3.82 | 3.82 |
| 474.59 | 4.79 | 4.79 |
| 488.61 | 5.18 | 5.18 |
| 488.61 | 4.93 | 4.93 |
| 436.49 | 3.20 | 3.20 |
| 436.49 | 3.20 | 3.20 |
| 436.49 | 3.20 | 3.20 |
| 450.52 | 3.59 | 3.59 |
| 449.54 | 3.12 | 3.12 |
| 449.54 | 3.12 | 3.12 |
| 449.54 | 3.12 | 3.12 |
| 475.57 | 3.65 | 3.65 |
| 489.60 | 4.04 | 4.04 |
| 477.59 | 3.68 | 3.68 |
| 481.60 | 3.71 | 3.71 |