Basic Information
ID: ALA3374011
Type: Binding
Description: Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured after 1 hr in presence of [gamma-33P]ATP by scintillation counting analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3374011
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 259.31 | 2.41 | 2.41 |
| 302.34 | 1.09 | 1.09 |
| 342.33 | 2.11 | 2.11 |
| 338.39 | 0.50 | 0.50 |
| 302.34 | 1.09 | 1.09 |
| 327.35 | 0.98 | 0.98 |
| 338.39 | 0.50 | 0.50 |
| 338.39 | 0.50 | 0.50 |
| 366.45 | 1.28 | 1.28 |
| 380.47 | 1.53 | 1.53 |
| 394.50 | 1.92 | 1.92 |
| 394.50 | 1.78 | 1.78 |
| 372.45 | 1.86 | 1.86 |
| 414.54 | 2.88 | 2.88 |
| 428.56 | 3.27 | 3.27 |
| 397.46 | 1.75 | 1.75 |
| 428.56 | 3.13 | 3.13 |
| 373.44 | 1.25 | 1.25 |
| 388.46 | 0.83 | 0.83 |
| 389.44 | 0.54 | 0.54 |
| 460.56 | 1.43 | 1.43 |
| 458.55 | 0.82 | 0.82 |
| 458.55 | 1.09 | 1.09 |
| 471.59 | 1.00 | 1.00 |
| 352.42 | 0.53 | 0.53 |
| 373.44 | 1.25 | 1.25 |