Basic Information
ID: ALA3375263
Type: Binding
Description: Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3375263
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 385.41 | 5.99 | 5.99 |
| 401.56 | 5.30 | 5.30 |
| 398.49 | 6.08 | 6.08 |
| 408.55 | 6.56 | 6.56 |
| 404.40 | 5.17 | 5.17 |
| 464.49 | 5.76 | 5.76 |
| 384.49 | 4.77 | 4.77 |
| 406.46 | 6.11 | 6.11 |
| 423.56 | 6.01 | 6.01 |
| 456.47 | 6.99 | 6.99 |
| 461.53 | 7.98 | 7.98 |
| 435.58 | 5.59 | 5.59 |
| 415.59 | 5.61 | 5.61 |
| 420.52 | 6.69 | 6.69 |
| 416.53 | 6.53 | 6.53 |
| 402.50 | 6.28 | 6.28 |
| 420.52 | 5.82 | 5.82 |
| 385.48 | 4.37 | 4.37 |
| 420.56 | 6.43 | 6.43 |
| 412.51 | 6.39 | 6.39 |
| 387.53 | 4.91 | 4.91 |
| 418.50 | 5.98 | 5.98 |
| 318.42 | 4.58 | 4.58 |
| 382.47 | 4.62 | 4.62 |
| 378.44 | 4.49 | 4.49 |
| 422.92 | 6.62 | 6.62 |
| 433.47 | 5.88 | 5.88 |
| 394.48 | 5.33 | 5.33 |
| 408.55 | 6.56 | 6.56 |
| 457.46 | 6.38 | 6.38 |
| 419.53 | 6.19 | 6.19 |
| 380.54 | 4.10 | 4.10 |
| 394.52 | 6.25 | 6.25 |
| 380.50 | 5.96 | 5.96 |
| 408.51 | 5.24 | 5.24 |
| 361.49 | 5.03 | 5.03 |
| 456.47 | 6.99 | 6.99 |
| 331.46 | 5.50 | 5.50 |
| 381.48 | 4.90 | 4.90 |
| 430.56 | 7.09 | 7.09 |
| 323.47 | 5.25 | 5.25 |
| 462.52 | 7.27 | 7.27 |
| 392.51 | 6.00 | 6.00 |
| 394.52 | 6.25 | 6.25 |
| 396.49 | 5.18 | 5.18 |
| 402.55 | 4.69 | 4.69 |
| 380.50 | 5.94 | 5.94 |
| 456.47 | 6.99 | 6.99 |
| 410.52 | 5.95 | 5.95 |
| 436.58 | 7.16 | 7.16 |
| 421.55 | 5.54 | 5.54 |
| 338.50 | 4.33 | 4.33 |
| 373.50 | 4.52 | 4.52 |
| 395.51 | 5.52 | 5.52 |
| 436.58 | 7.16 | 7.16 |
| 438.48 | 6.91 | 6.91 |
| 467.37 | 6.73 | 6.73 |
| 392.41 | 4.58 | 4.58 |
| 426.59 | 6.66 | 6.66 |
| 399.44 | 6.30 | 6.30 |
| 379.39 | 5.93 | 5.93 |
| 423.39 | 5.66 | 5.66 |
| 409.41 | 5.94 | 5.94 |
| 397.38 | 6.07 | 6.07 |
| 413.83 | 6.58 | 6.58 |
| 447.38 | 6.95 | 6.95 |
| 448.28 | 7.23 | 7.23 |
| 404.40 | 5.80 | 5.80 |
| 455.48 | 7.59 | 7.59 |
| 489.93 | 8.25 | 8.25 |
| 489.93 | 8.25 | 8.25 |
| 524.37 | 8.90 | 8.90 |
| 456.47 | 6.99 | 6.99 |
| 524.47 | 8.01 | 8.01 |
| 397.48 | 4.14 | 4.14 |
| 383.50 | 5.37 | 5.37 |
| 396.50 | 4.91 | 4.91 |
| 398.47 | 3.76 | 3.76 |
| 412.54 | 5.50 | 5.50 |
| 390.52 | 4.77 | 4.77 |
| 391.53 | 4.77 | 4.77 |
| 419.58 | 5.50 | 5.50 |
| 386.50 | 4.77 | 4.77 |
| 393.54 | 4.77 | 4.77 |