Basic Information
ID: ALA3375358
Type: Binding
Description: Inhibition of human full length VCP (2 to 806 residues) expressed in High5 insect cells assessed as reduction in ATPase activity by measuring ADP formation by NADH coupled assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3375358
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 336.42 | 4.44 | 4.44 |
| 467.49 | 4.32 | 4.32 |
| 292.41 | 4.74 | 4.74 |
| 350.44 | 4.49 | 4.49 |
| 322.39 | 4.30 | 4.30 |
| 274.35 | 3.02 | 3.02 |
| 368.41 | 3.12 | 3.12 |
| 319.36 | 3.76 | 3.76 |
| 319.36 | 3.76 | 3.76 |
| 325.41 | 3.75 | 3.75 |
| 311.39 | 3.45 | 3.45 |
| 339.44 | 4.06 | 4.06 |
| 355.44 | 3.76 | 3.76 |
| 339.44 | 4.06 | 4.06 |
| 359.86 | 4.41 | 4.41 |
| 355.44 | 3.76 | 3.76 |
| 339.44 | 4.06 | 4.06 |
| 359.86 | 4.41 | 4.41 |
| 343.40 | 3.89 | 3.89 |
| 355.44 | 3.76 | 3.76 |
| 387.48 | 5.11 | 5.11 |
| 401.51 | 5.42 | 5.42 |
| 405.47 | 5.25 | 5.25 |
| 421.93 | 5.77 | 5.77 |
| 417.51 | 5.12 | 5.12 |
| 401.51 | 5.42 | 5.42 |
| 405.47 | 5.25 | 5.25 |
| 421.93 | 5.77 | 5.77 |
| 417.51 | 5.12 | 5.12 |
| 465.58 | 4.52 | 4.52 |
| 432.48 | 5.02 | 5.02 |
| 428.50 | 6.06 | 6.06 |
| 401.51 | 5.42 | 5.42 |
| 405.47 | 5.25 | 5.25 |
| 421.93 | 5.77 | 5.77 |
| 417.51 | 5.12 | 5.12 |
| 465.58 | 4.52 | 4.52 |
| 432.48 | 5.02 | 5.02 |
| 402.50 | 4.70 | 4.70 |
| 447.50 | 4.60 | 4.60 |
| 426.52 | 5.59 | 5.59 |
| 377.44 | 4.71 | 4.71 |
| 388.47 | 4.51 | 4.51 |
| 388.47 | 4.51 | 4.51 |
| 377.44 | 4.71 | 4.71 |
| 416.53 | 5.06 | 5.06 |
| 402.50 | 5.19 | 5.19 |
| 408.55 | 5.19 | 5.19 |
| 396.49 | 3.28 | 3.28 |
| 415.54 | 4.46 | 4.46 |
| 429.57 | 4.72 | 4.72 |
| 493.63 | 4.05 | 4.05 |
| 547.60 | 4.94 | 4.94 |
| 430.56 | 3.96 | 3.96 |
| 429.57 | 4.77 | 4.77 |
| 433.53 | 4.60 | 4.60 |
| 449.99 | 5.11 | 5.11 |
| 494.44 | 5.22 | 5.22 |
| 445.57 | 4.47 | 4.47 |
| 429.57 | 4.77 | 4.77 |
| 433.53 | 4.60 | 4.60 |
| 449.99 | 5.11 | 5.11 |
| 445.57 | 4.47 | 4.47 |
| 460.54 | 4.37 | 4.37 |
| 494.62 | 3.11 | 3.11 |
| 429.57 | 4.77 | 4.77 |
| 433.53 | 4.60 | 4.60 |
| 449.99 | 5.11 | 5.11 |
| 445.57 | 4.47 | 4.47 |
| 494.62 | 3.11 | 3.11 |
| 493.63 | 3.86 | 3.86 |
| 433.53 | 4.60 | 4.60 |
| 457.58 | 4.66 | 4.66 |
| 431.54 | 4.16 | 4.16 |
| 445.57 | 3.95 | 3.95 |
| 445.57 | 4.47 | 4.47 |
| 429.57 | 4.77 | 4.77 |
| 483.54 | 5.48 | 5.48 |
| 472.59 | 4.42 | 4.42 |
| 445.57 | 3.95 | 3.95 |
| 457.58 | 4.66 | 4.66 |
| 449.99 | 5.11 | 5.11 |
| 483.54 | 5.48 | 5.48 |
| 459.59 | 4.86 | 4.86 |
| 433.53 | 4.60 | 4.60 |
| 455.56 | 5.21 | 5.21 |
| 455.57 | 4.34 | 4.34 |
| 471.63 | 5.67 | 5.67 |
| 454.58 | 4.94 | 4.94 |
| 416.53 | 3.85 | 3.85 |
| 421.57 | 4.52 | 4.52 |
| 405.50 | 4.05 | 4.05 |