Basic Information
ID: ALA3375591
Type: Functional
Description: Inhibition of LPS-induced TNFalpha release in human PBMC preincubated for 30 mins before LPS stimulation measured after 18 hrs by TR-FRET assay
Organism: Homo sapiens
Cell type: PBMC
Activity Charts
Bioactivity
Activity Types for Assay ALA3375591
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.17 | 3.66 | 3.66 |
| 357.19 | 3.67 | 3.67 |
| 326.18 | 3.83 | 3.83 |
| 356.20 | 3.84 | 3.84 |
| 370.23 | 4.23 | 4.23 |
| 396.27 | 4.62 | 4.62 |
| 410.30 | 5.15 | 5.15 |
| 432.30 | 5.41 | 5.41 |
| 446.33 | 5.45 | 5.45 |
| 460.36 | 5.84 | 5.84 |
| 462.33 | 5.16 | 5.16 |
| 503.38 | 4.81 | 4.81 |
| 490.34 | 5.15 | 5.15 |
| 400.21 | 3.29 | 3.29 |
| 489.36 | 4.53 | 4.53 |
| 475.33 | 4.85 | 4.85 |
| 489.36 | 4.87 | 4.87 |
| 443.28 | 2.32 | 2.32 |
| 457.31 | 2.97 | 2.97 |
| 441.31 | 3.74 | 3.74 |
| 505.35 | 3.76 | 3.76 |
| 399.23 | 2.70 | 2.70 |