ID: ALA3375790
Type: Binding
Description: Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation counting
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA3375790
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
423.59 | 3.79 | 3.79 |
384.46 | 1.98 | 1.98 |
425.56 | 2.94 | 2.94 |
297.38 | 3.26 | 3.26 |
221.28 | 1.59 | 1.59 |
263.37 | 2.83 | 2.83 |
277.39 | 3.22 | 3.22 |
277.39 | 3.14 | 3.14 |
291.42 | 3.39 | 3.39 |
369.49 | 3.84 | 3.84 |
482.61 | 3.44 | 3.44 |
277.39 | 3.14 | 3.14 |
291.42 | 3.39 | 3.39 |
289.40 | 3.48 | 3.48 |
287.39 | 2.81 | 2.81 |
288.38 | 2.70 | 2.70 |
364.47 | 3.63 | 3.63 |
386.52 | 2.52 | 2.52 |
368.51 | 4.01 | 4.01 |
390.55 | 3.10 | 3.10 |
339.46 | 4.50 | 4.50 |
397.50 | 4.29 | 4.29 |
397.50 | 4.29 | 4.29 |
397.50 | 4.29 | 4.29 |
340.45 | 3.89 | 3.89 |
438.60 | 4.33 | 4.33 |
425.56 | 3.73 | 3.73 |
461.59 | 3.42 | 3.42 |