Basic Information
ID: ALA3377096
Type: Binding
Description: Inhibition of JAK2 in human PBMC expressing CD14 assessed as inhibition of GM-CSF-stimulated STAT5a phosphorylation after 30 mins by flow cytometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3377096
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 338.39 | 0.50 | 0.50 |
| 366.45 | 1.28 | 1.28 |
| 380.47 | 1.53 | 1.53 |
| 394.50 | 1.92 | 1.92 |
| 394.50 | 1.78 | 1.78 |
| 372.45 | 1.86 | 1.86 |
| 414.54 | 2.88 | 2.88 |
| 428.56 | 3.27 | 3.27 |
| 397.46 | 1.75 | 1.75 |
| 428.56 | 3.13 | 3.13 |