Basic Information
ID: ALA3377191
Type: Functional
Description: Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells assessed as dissociation half-life at 5 to 10 times IC50 after 2 hrs by radio-labelled [35S]-GTPgammaS binding assay
Organism: Homo sapiens
Cell type: CHO.K1
Activity Charts
Bioactivity
Activity Types for Assay ALA3377191
T1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.51 | 2.59 | 2.59 |
| 468.53 | 2.60 | 2.60 |
| 506.50 | 3.61 | 3.61 |
| 482.51 | 2.29 | 2.29 |
| 496.54 | 2.38 | 2.38 |
| 495.56 | 1.95 | 1.95 |
| 456.50 | 2.73 | 2.73 |
| 468.53 | 2.60 | 2.60 |
| 517.40 | 3.35 | 3.35 |
| 463.52 | 2.46 | 2.46 |
| 468.53 | 2.60 | 2.60 |
| 456.50 | 2.73 | 2.73 |
| 456.50 | 2.73 | 2.73 |
| 472.95 | 3.24 | 3.24 |
| 468.53 | 2.60 | 2.60 |
| 495.56 | 1.95 | 1.95 |
| 456.50 | 2.73 | 2.73 |
| 472.95 | 3.24 | 3.24 |
| 468.53 | 2.60 | 2.60 |
| 522.50 | 3.49 | 3.49 |
| 486.52 | 2.74 | 2.74 |
| 452.53 | 3.15 | 3.15 |
| 452.53 | 3.15 | 3.15 |
| 390.46 | 1.55 | 1.55 |
| 444.55 | 2.86 | 2.86 |
| 447.51 | 0.78 | 0.78 |
| 481.57 | 2.58 | 2.58 |
| 376.43 | 1.16 | 1.16 |
| 438.51 | 2.59 | 2.59 |
| 452.53 | 2.73 | 2.73 |
| 379.42 | 1.40 | 1.40 |
| 423.51 | 2.52 | 2.52 |
| 402.45 | 2.99 | 2.99 |
| 404.47 | 2.84 | 2.84 |
| 388.47 | 3.35 | 3.35 |
| 424.50 | 4.58 | 4.58 |
| 390.44 | 3.55 | 3.55 |
| 452.53 | 2.93 | 2.93 |
| 528.63 | 4.50 | 4.50 |
| 480.59 | 3.71 | 3.71 |
| 534.56 | 4.25 | 4.25 |
| 466.56 | 3.37 | 3.37 |
| 484.55 | 3.51 | 3.51 |
| 514.58 | 3.52 | 3.52 |
| 454.94 | 4.51 | 4.51 |
| 436.49 | 3.15 | 3.15 |
| 450.52 | 3.16 | 3.16 |
| 486.50 | 4.01 | 4.01 |