Basic Information
ID: ALA3377637
Type: Binding
Description: Inhibition of human recombinant caspase 1 using Ac-YVAD-AMC substrate assessed as accumulation of cleaved fluorogenic product
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3377637
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 324.36 | 0.62 | 0.62 |
| 338.39 | 0.65 | 0.65 |
| 352.41 | 1.04 | 1.04 |
| 366.44 | 1.43 | 1.43 |
| 380.47 | 1.82 | 1.82 |
| 398.46 | 1.77 | 1.77 |
| 450.25 | 1.23 | 1.23 |
| 464.28 | 1.25 | 1.25 |
| 478.31 | 1.64 | 1.64 |
| 492.34 | 2.03 | 2.03 |
| 506.36 | 2.42 | 2.42 |
| 510.33 | 1.98 | 1.98 |
| 524.35 | 2.37 | 2.37 |
| 522.36 | 1.39 | 1.39 |
| 403.25 | 1.38 | 1.38 |
| 417.28 | 1.41 | 1.41 |
| 431.31 | 1.80 | 1.80 |
| 445.34 | 2.19 | 2.19 |
| 459.36 | 2.58 | 2.58 |
| 463.33 | 2.14 | 2.14 |
| 477.35 | 2.53 | 2.53 |
| 475.36 | 1.55 | 1.55 |
| 358.80 | 1.27 | 1.27 |
| 414.91 | 2.47 | 2.47 |
| 418.87 | 2.03 | 2.03 |
| 342.35 | 0.76 | 0.76 |
| 398.46 | 1.95 | 1.95 |
| 402.42 | 1.51 | 1.51 |