Assay Report Card

Basic Information

ID: ALA3378582

Type: Functional

Description: Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobilization by fluorescence assay

Organism: Rattus norvegicus

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
348.384.004.00
348.384.004.00
362.404.004.00
380.394.144.14
380.394.144.14
380.394.144.14
254.291.951.95
272.282.092.09
272.282.092.09
288.732.602.60
340.403.603.60
356.402.832.83
362.404.004.00
366.374.144.14
367.363.543.54
344.413.863.86
254.291.951.95
272.282.092.09
328.393.453.45
326.373.213.21
348.384.004.00
366.374.144.14
367.363.543.54
362.404.004.00