ID: ALA3378582
Type: Functional
Description: Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobilization by fluorescence assay
Organism: Rattus norvegicus
Cell type: HEK293
Bioactivity
Activity Types for Assay ALA3378582
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
348.38 | 4.00 | 4.00 |
348.38 | 4.00 | 4.00 |
362.40 | 4.00 | 4.00 |
380.39 | 4.14 | 4.14 |
380.39 | 4.14 | 4.14 |
380.39 | 4.14 | 4.14 |
254.29 | 1.95 | 1.95 |
272.28 | 2.09 | 2.09 |
272.28 | 2.09 | 2.09 |
288.73 | 2.60 | 2.60 |
340.40 | 3.60 | 3.60 |
356.40 | 2.83 | 2.83 |
362.40 | 4.00 | 4.00 |
366.37 | 4.14 | 4.14 |
367.36 | 3.54 | 3.54 |
344.41 | 3.86 | 3.86 |
254.29 | 1.95 | 1.95 |
272.28 | 2.09 | 2.09 |
328.39 | 3.45 | 3.45 |
326.37 | 3.21 | 3.21 |
348.38 | 4.00 | 4.00 |
366.37 | 4.14 | 4.14 |
367.36 | 3.54 | 3.54 |
362.40 | 4.00 | 4.00 |