Basic Information
ID: ALA3378583
Type: Functional
Description: Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobilization at 30 uM by fluorescence assay relative to glutamate
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3378583
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.38 | 4.00 | 4.00 |
| 254.29 | 1.95 | 1.95 |
| 268.32 | 2.29 | 2.29 |
| 338.45 | 4.09 | 4.09 |
| 348.38 | 4.00 | 4.00 |
| 362.40 | 4.00 | 4.00 |
| 380.39 | 4.14 | 4.14 |
| 380.39 | 4.14 | 4.14 |
| 326.37 | 3.09 | 3.09 |
| 380.39 | 4.14 | 4.14 |
| 344.41 | 3.86 | 3.86 |
| 254.29 | 1.95 | 1.95 |
| 272.28 | 2.09 | 2.09 |
| 272.28 | 2.09 | 2.09 |
| 288.73 | 2.60 | 2.60 |
| 288.73 | 2.60 | 2.60 |
| 288.73 | 2.60 | 2.60 |
| 255.28 | 1.34 | 1.34 |
| 255.28 | 1.34 | 1.34 |
| 286.31 | 2.43 | 2.43 |
| 328.39 | 3.45 | 3.45 |
| 326.37 | 3.21 | 3.21 |
| 340.40 | 3.60 | 3.60 |
| 356.40 | 2.83 | 2.83 |
| 362.40 | 4.00 | 4.00 |
| 366.37 | 4.14 | 4.14 |
| 367.36 | 3.54 | 3.54 |
| 220.27 | 1.55 | 1.55 |
| 332.35 | 3.74 | 3.74 |
| 344.41 | 3.86 | 3.86 |
| 345.40 | 3.25 | 3.25 |
| 254.29 | 1.95 | 1.95 |
| 272.28 | 2.09 | 2.09 |
| 286.31 | 2.43 | 2.43 |
| 328.39 | 3.45 | 3.45 |
| 326.37 | 3.21 | 3.21 |
| 348.38 | 4.00 | 4.00 |
| 366.37 | 4.14 | 4.14 |
| 367.36 | 3.54 | 3.54 |
| 362.40 | 4.00 | 4.00 |
| 254.29 | 1.95 | 1.95 |
| 268.32 | 2.29 | 2.29 |
| 338.45 | 4.09 | 4.09 |