ID: ALA3378918
Type: Binding
Description: Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding potential of -80 mV by electrophysiology
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA3378918
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
272.26 | 2.41 | 2.41 |
256.26 | 2.70 | 2.70 |
256.26 | 2.70 | 2.70 |
311.73 | 3.30 | 3.30 |
376.48 | 4.31 | 4.31 |
402.90 | 4.35 | 4.35 |
256.26 | 2.70 | 2.70 |
256.26 | 2.70 | 2.70 |
256.26 | 2.70 | 2.70 |
256.26 | 2.70 | 2.70 |
256.26 | 2.70 | 2.70 |
272.26 | 2.41 | 2.41 |
272.26 | 2.41 | 2.41 |
288.25 | 2.11 | 2.11 |
256.26 | 2.70 | 2.70 |
272.26 | 2.41 | 2.41 |
328.36 | 3.62 | 3.62 |
286.28 | 2.71 | 2.71 |
300.31 | 3.01 | 3.01 |
316.31 | 2.72 | 2.72 |
295.29 | 3.18 | 3.18 |