Basic Information
ID: ALA3378921
Type: Binding
Description: Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of ACh-induced current at holding potential of -80 mV measured as ACh EC50 at 1 uM by electrophysiology (Rvb = 176 uM)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3378921
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 256.26 | 2.70 | 2.70 |
| 272.26 | 2.41 | 2.41 |