Basic Information
ID: ALA3379466
Type: Binding
Description: Inhibition of P-gp-mediated doxorubicin efflux in human HL60/MDR cells assessed as intracellular doxorubicin accumulation at 25 uM preincubated for 15 mins measured after 60 mins by flow cytometry
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HL60/MDR
Target: Unchecked(ALA612545)
Document: ALA3351498
Inhibition of P-gp-mediated doxorubicin efflux in human HL60/MDR cells assessed as intracellular doxorubicin accumulation at 25 uM preincubated for 15 mins measured after 60 mins by flow cytometry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3379466
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 388.46 | 4.17 | 4.17 |
| 400.47 | 4.49 | 4.49 |
| 432.51 | 3.89 | 3.89 |
| 384.43 | 4.20 | 4.20 |
| 514.57 | 4.61 | 4.61 |
| 416.51 | 4.78 | 4.78 |
| 400.47 | 4.49 | 4.49 |
| 536.58 | 4.96 | 4.96 |
| 400.47 | 4.49 | 4.49 |
| 500.54 | 4.31 | 4.31 |
| 500.59 | 4.75 | 4.75 |
| 416.47 | 3.60 | 3.60 |