Basic Information
ID: ALA3379760
Type: Binding
Description: Antagonist activity at C-terminal 6xHis-tagged LFA-1 LBD (unknown origin) expressed in Escherichia coli assessed as inhibition of interaction with ICAM-1 preincubated for 30 mins followed by ICAM-1 addition measured after 60 mins by ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3379760
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 749.64 | 6.01 | 6.01 |
| 801.69 | 5.44 | 5.44 |
| 739.63 | 6.04 | 6.04 |
| 791.68 | 5.47 | 5.47 |
| 540.50 | 4.52 | 4.52 |
| 670.74 | 5.25 | 5.25 |
| 670.74 | 5.25 | 5.25 |
| 656.71 | 4.69 | 4.69 |
| 670.74 | 4.73 | 4.73 |
| 594.64 | 3.51 | 3.51 |
| 712.56 | 5.99 | 5.99 |
| 668.55 | 6.53 | 6.53 |
| 620.51 | 6.31 | 6.31 |
| 748.62 | 5.54 | 5.54 |
| 1396.48 | ||
| 1432.53 |