Basic Information
ID: ALA3379762
Type: Binding
Description: Allosteric antagonist activity at LFA-1 K287C/K294C double mutant (unknown origin) transfected in human K562 cells assessed as inhibition of cell adhesion to ICAM-1 at 50 uM incubated for 30 mins under dark condition by microplate fluorimetric analysis in absence of DTT
Organism: Homo sapiens
Cell type: K562
Activity Charts
Bioactivity
Activity Types for Assay ALA3379762
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 749.64 | 6.01 | 6.01 |
| 801.69 | 5.44 | 5.44 |
| 739.63 | 6.04 | 6.04 |
| 791.68 | 5.47 | 5.47 |