Basic Information
ID: ALA3382019
Type: Binding
Description: Inhibition of GARFTase in human KB cells assessed as reduction in [14C]glycine incorporation into [14C]formyl GAR incubated for 15 hrs by ion-exchange chromatography
Format: BAO_0000219
Organism: Homo sapiens
Cell type: KB
Target: GAR transformylase(ALA3972)
Document: ALA3351552
Inhibition of GARFTase in human KB cells assessed as reduction in [14C]glycine incorporation into [14C]formyl GAR incubated for 15 hrs by ion-exchange chromatography: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3382019
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 447.47 | 1.12 | 1.12 |
| 461.50 | 1.51 | 1.51 |