Basic Information
ID: ALA3383863
Type: Binding
Description: Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP at 10 uM after 20 mins by scintillation proximity assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3383863
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 275.35 | 2.62 | 2.62 |
| 265.72 | 4.40 | 4.40 |
| 254.31 | 3.05 | 3.05 |
| 244.27 | 1.15 | 1.15 |
| 266.71 | 3.79 | 3.79 |
| 266.71 | 3.79 | 3.79 |
| 306.71 | 4.00 | 4.00 |
| 187.27 | 3.23 | 3.23 |
| 322.77 | 4.36 | 4.36 |
| 315.18 | 4.64 | 4.64 |
| 314.29 | 4.35 | 4.35 |
| 280.74 | 3.98 | 3.98 |
| 264.28 | 3.47 | 3.47 |
| 314.29 | 4.35 | 4.35 |
| 280.74 | 3.98 | 3.98 |
| 280.74 | 3.98 | 3.98 |
| 280.74 | 3.98 | 3.98 |
| 344.62 | 5.16 | 5.16 |
| 344.62 | 5.16 | 5.16 |
| 344.62 | 5.16 | 5.16 |
| 280.74 | 3.98 | 3.98 |
| 280.74 | 3.98 | 3.98 |
| 280.74 | 3.98 | 3.98 |
| 280.74 | 3.98 | 3.98 |
| 264.28 | 3.47 | 3.47 |
| 379.06 | 5.82 | 5.82 |
| 344.62 | 5.16 | 5.16 |
| 344.62 | 5.16 | 5.16 |
| 344.62 | 5.16 | 5.16 |
| 358.64 | 5.30 | 5.30 |
| 358.64 | 5.30 | 5.30 |
| 307.80 | 5.52 | 5.52 |
| 307.80 | 5.52 | 5.52 |
| 307.80 | 5.52 | 5.52 |
| 280.74 | 3.98 | 3.98 |
| 310.72 | 4.31 | 4.31 |
| 310.72 | 4.31 | 4.31 |
| 265.72 | 4.40 | 4.40 |
| 264.67 | 3.62 | 3.62 |
| 264.67 | 3.62 | 3.62 |
| 306.71 | 4.00 | 4.00 |
| 271.75 | 4.46 | 4.46 |
| 271.75 | 4.46 | 4.46 |
| 266.71 | 3.79 | 3.79 |
| 266.71 | 3.79 | 3.79 |
| 266.71 | 3.79 | 3.79 |
| 266.71 | 3.79 | 3.79 |
| 274.30 | 3.34 | 3.34 |
| 322.77 | 4.36 | 4.36 |
| 322.77 | 4.36 | 4.36 |
| 250.75 | 3.66 | 3.66 |
| 250.75 | 3.66 | 3.66 |
| 247.28 | 2.84 | 2.84 |
| 189.24 | 2.02 | 2.02 |
| 322.39 | 5.12 | 5.12 |
| 263.37 | 4.90 | 4.90 |
| 261.31 | 3.03 | 3.03 |
| 217.29 | 3.24 | 3.24 |
| 202.28 | 2.82 | 2.82 |
| 217.29 | 3.24 | 3.24 |
| 294.36 | 3.77 | 3.77 |
| 288.33 | 3.78 | 3.78 |
| 337.24 | 4.06 | 4.06 |