Basic Information
ID: ALA3384495
Type: ADME
Description: Therapeutic index, ratio of LC50 for Sprague-Dawley rat by rotarod test to HD50 for hypnotic activity in iv dosed Sprague-Dawley rat
Activity Charts
Bioactivity
Activity Types for Assay ALA3384495
TI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 178.27 | 3.64 | 3.64 |
| 337.42 | 2.44 | 2.44 |
| 341.38 | 2.19 | 2.19 |
| 355.41 | 2.58 | 2.58 |
| 355.41 | 2.58 | 2.58 |
| 395.35 | 2.73 | 2.73 |
| 409.38 | 3.12 | 3.12 |
| 355.41 | 2.58 | 2.58 |
| 369.43 | 2.97 | 2.97 |
| 369.43 | 2.97 | 2.97 |
| 409.38 | 3.12 | 3.12 |
| 423.40 | 3.51 | 3.51 |
| 341.38 | 2.19 | 2.19 |
| 355.41 | 2.58 | 2.58 |
| 355.41 | 2.58 | 2.58 |
| 395.35 | 2.73 | 2.73 |
| 409.38 | 3.12 | 3.12 |
| 355.41 | 2.58 | 2.58 |
| 369.43 | 2.97 | 2.97 |
| 369.43 | 2.97 | 2.97 |
| 409.38 | 3.12 | 3.12 |
| 423.40 | 3.51 | 3.51 |
| 341.38 | 2.19 | 2.19 |
| 355.41 | 2.58 | 2.58 |
| 355.41 | 2.58 | 2.58 |
| 395.35 | 2.73 | 2.73 |
| 409.38 | 3.12 | 3.12 |
| 355.41 | 2.58 | 2.58 |
| 369.43 | 2.97 | 2.97 |
| 369.43 | 2.97 | 2.97 |
| 409.38 | 3.12 | 3.12 |
| 423.40 | 3.51 | 3.51 |
| 383.46 | 3.36 | 3.36 |
| 383.46 | 3.36 | 3.36 |
| 383.46 | 3.36 | 3.36 |
| 351.44 | 2.83 | 2.83 |