Basic Information
ID: ALA3384556
Type: Functional
Description: Ex vivo inhibition of 11beta-HSD1 in po dosed cynomolgus monkey mesenteric fat assessed as decrease in [3H]-cortisol production at 10 mg/kg, po after 4 hrs by LC/MS/MS
Format: BAO_0000218
Organism: Macaca fascicularis
Target: Cynomolgus monkey(ALA613847)
Document: ALA3352714
Ex vivo inhibition of 11beta-HSD1 in po dosed cynomolgus monkey mesenteric fat assessed as decrease in [3H]-cortisol production at 10 mg/kg, po after 4 hrs by LC/MS/MS: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3384556
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 449.50 | 1.42 | 1.42 |
| 522.54 | 5.18 | 5.18 |
| 389.78 | 3.81 | 3.81 |