Basic Information
ID: ALA3385093
Type: Binding
Description: Inhibition of IDH1 R132H mutant (unknown origin) assessed as inhibition of [3C]2-hydroxyglutarate formation after 45 mins by LC-MS biochemical assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3385093
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.92 | 4.53 | 4.53 |
| 442.88 | 4.36 | 4.36 |
| 537.56 | 4.80 | 4.80 |
| 468.58 | 3.84 | 3.84 |