Basic Information
ID: ALA3385094
Type: Binding
Description: Inhibition of IDH1 R132H mutant (unknown origin) using a-ketoglutarate as substrate by fluorescence biochemical assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Isocitrate dehydrogenase [NADP] cytoplasmic(ALA2007625)
Document: ALA3352118
Inhibition of IDH1 R132H mutant (unknown origin) using a-ketoglutarate as substrate by fluorescence biochemical assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3385094
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.92 | 4.53 | 4.53 |
| 442.88 | 4.36 | 4.36 |
| 537.56 | 4.80 | 4.80 |
| 468.58 | 3.84 | 3.84 |