Assay Report Card

Basic Information

ID: ALA3385942

Type: ADME

Description: Permeability in MDCK2-MDR1 cells assessed as cell associated fraction by measuring mass fraction extracted from cell monolayer by methanol wash after 1 hr flux in apical to basolateral direction at 5 uM in presence of 4.3 mg/ml BSA and in presence of P-gp inhibitor LSN335984 by mass spectrometry

Organism: Canis lupus familiaris

Cell type: MDCK-II

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
613.13
629.20