Basic Information
ID: ALA3387261
Type: Functional
Description: Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monophosphate production incubated for 15 to 60 mins before I-BOP addition by HTRF assay
Organism: Homo sapiens
Cell type: HEK293-A
Activity Charts
Bioactivity
Activity Types for Assay ALA3387261
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 367.85 | 2.88 | 2.88 |
| 407.92 | 3.50 | 3.50 |
| 379.87 | 2.80 | 2.80 |
| 346.47 | 5.28 | 5.28 |
| 482.00 | 4.96 | 4.96 |
| 488.05 | 5.38 | 5.38 |
| 445.97 | 4.14 | 4.14 |
| 508.04 | 5.28 | 5.28 |
| 526.03 | 5.42 | 5.42 |
| 538.07 | 5.29 | 5.29 |
| 592.20 | 7.01 | 7.01 |
| 536.09 | 5.89 | 5.89 |
| 522.07 | 5.36 | 5.36 |