Basic Information
ID: ALA3387263
Type: Functional
Description: Reversible antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monophosphate production at 1 uM incubated for 15 to 60 mins before I-BOP addition and measured after 4 consecutive drug washout by HTRF assay
Organism: Homo sapiens
Cell type: HEK293-A
Activity Charts
Bioactivity
Activity Types for Assay ALA3387263
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 367.85 | 2.88 | 2.88 |
| 379.87 | 2.80 | 2.80 |
| 346.47 | 5.28 | 5.28 |
| 488.05 | 5.38 | 5.38 |
| 445.97 | 4.14 | 4.14 |