Basic Information
ID: ALA3387264
Type: Functional
Description: Irreversible antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monophosphate production at 1 uM incubated for 15 to 60 mins before I-BOP addition and measured after 4 consecutive drug washout by HTRF assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293-A
Target: Thromboxane A2 receptor(ALA2069)
Document: ALA3351871
Irreversible antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monophosphate production at 1 uM incubated for 15 to 60 mins before I-BOP addition and measured after 4 consecutive drug washout by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3387264
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 538.07 | 5.29 | 5.29 |
| 536.09 | 5.89 | 5.89 |