Basic Information
ID: ALA3387266
Type: Functional
Description: Irreversible antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monophosphate production at 1 uM incubated for 15 to 60 mins before I-BOP addition and measured after 6 consecutive drug washout by HTRF assay
Organism: Homo sapiens
Cell type: HEK293-A
Activity Charts
Bioactivity
Activity Types for Assay ALA3387266
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 482.00 | 4.96 | 4.96 |
| 508.04 | 5.28 | 5.28 |
| 526.03 | 5.42 | 5.42 |
| 536.09 | 5.89 | 5.89 |
| 522.07 | 5.36 | 5.36 |