Irreversible antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced ino...

Basic Information

ID: ALA3387267

Type: Functional

Description: Irreversible antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monophosphate production at 1 uM at 4 degC incubated for 15 to 60 mins before I-BOP addition and measured after 6 consecutive drug washout by HTRF assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293-A

Target:  Thromboxane A2 receptor(ALA2069)

Document:  ALA3351871

Irreversible antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monophosphate production at 1 uM at 4 degC incubated for 15 to 60 mins before I-BOP addition and measured after 6 consecutive drug washout by HTRF assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
536.095.895.89