Basic Information
ID: ALA3387317
Type: Binding
Description: Inhibition of PTP1B (unknown origin) expressed in antiCD3-antibody-stimulated human Jurkat T cells over-expressing STEP assessed as activation of TCR-mediated and IL-2 promoter driven NFAT/AP1 transcriptional activation incubated for 1 hr by dual luciferase reporter gene assay
Organism: Homo sapiens
Cell type: Jurkat
Activity Charts
Bioactivity
Activity Types for Assay ALA3387317
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 597.69 | 4.14 | 4.14 |
| 589.75 | 6.28 | 6.28 |