Basic Information
ID: ALA3387686
Type: Functional
Description: Antitrypanosomal activity against Trypanosoma brucei BSF427 expressing VSG118 infected in human MRC5 cells assessed as reduction cell viability incubated for 69 hrs by rezasurin dye based assay
Organism: Trypanosoma brucei
Strain: BSF427
Cell type: MRC5
Activity Charts
Bioactivity
Activity Types for Assay ALA3387686
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 495.44 | 3.62 | 3.62 |
| 413.12 | 3.91 | 3.91 |
| 481.41 | 3.31 | 3.31 |
| 481.41 | 3.31 | 3.31 |
| 467.38 | 3.00 | 3.00 |
| 537.52 | 4.51 | 4.51 |
| 537.52 | 4.51 | 4.51 |
| 494.45 | 4.22 | 4.22 |
| 493.46 | 5.28 | 5.28 |
| 509.46 | 3.96 | 3.96 |
| 438.34 | 3.28 | 3.28 |
| 470.43 | 2.74 | 2.74 |
| 474.46 | 3.32 | 3.32 |
| 405.57 | 2.02 | 2.02 |
| 473.47 | 4.81 | 4.81 |
| 404.58 | 3.50 | 3.50 |
| 459.44 | 4.47 | 4.47 |
| 390.55 | 3.16 | 3.16 |
| 487.50 | 5.20 | 5.20 |
| 418.61 | 3.89 | 3.89 |
| 473.47 | 4.86 | 4.86 |
| 404.58 | 3.55 | 3.55 |
| 427.15 | 3.93 | 3.93 |
| 509.46 | 3.64 | 3.64 |
| 440.57 | 2.33 | 2.33 |
| 453.61 | 3.25 | 3.25 |
| 467.64 | 3.28 | 3.28 |
| 488.49 | 3.35 | 3.35 |
| 502.51 | 3.74 | 3.74 |
| 484.45 | 4.78 | 4.78 |
| 512.51 | 5.56 | 5.56 |
| 487.50 | 4.83 | 4.83 |
| 418.61 | 3.53 | 3.53 |
| 501.52 | 5.22 | 5.22 |
| 523.48 | 5.43 | 5.43 |
| 537.50 | 5.47 | 5.47 |
| 555.49 | 5.77 | 5.77 |
| 509.45 | 5.08 | 5.08 |
| 524.47 | 3.94 | 3.94 |
| 523.48 | 5.47 | 5.47 |
| 537.50 | 5.82 | 5.82 |
| 539.48 | 4.81 | 4.81 |
| 511.47 | 5.43 | 5.43 |
| 539.48 | 4.81 | 4.81 |
| 553.50 | 5.20 | 5.20 |
| 539.48 | 4.81 | 4.81 |
| 553.50 | 5.20 | 5.20 |
| 550.50 | 4.47 | 4.47 |