Basic Information
ID: ALA3388197
Type: ADME
Description: Stability in pH 2.0 simulated gastric fluid assessed as compound degradation to beta-lactam ring open products at 1 uM after 60 mins by LC-MS/MS method
Format: BAO_0000221
Tissue: Stomach
Target: ADMET(ALA612558)
Document: ALA3351346
Stability in pH 2.0 simulated gastric fluid assessed as compound degradation to beta-lactam ring open products at 1 uM after 60 mins by LC-MS/MS method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3388197
Drug degradation
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 703.81 | 2.95 | 2.95 |
| 699.69 | 1.97 | 1.97 |
| 531.63 | 1.90 | 1.90 |
| 515.59 | 1.26 | 1.26 |
| 611.65 | 1.95 | 1.95 |
| 611.65 | 1.95 | 1.95 |
| 731.86 | 3.73 | 3.73 |
| 625.68 | 2.34 | 2.34 |
| 675.76 | 2.17 | 2.17 |
| 597.62 | 1.56 | 1.56 |
| 597.62 | 1.56 | 1.56 |
| 755.89 | 4.02 | 4.02 |
| 637.69 | 2.48 | 2.48 |
| 619.65 | 0.90 | 0.90 |
| 647.70 | 1.68 | 1.68 |
| 731.86 | 3.73 | 3.73 |
| 735.81 | 3.68 | 3.68 |
| 627.65 | 2.31 | 2.31 |
| 707.76 | 2.90 | 2.90 |
| 613.62 | 1.92 | 1.92 |
| 787.88 | 4.74 | 4.74 |
| 653.69 | 2.84 | 2.84 |
| 679.70 | 2.12 | 2.12 |
| 599.59 | 1.53 | 1.53 |
| 651.65 | 1.34 | 1.34 |
| 585.57 | 1.14 | 1.14 |
| 609.59 | 1.45 | 1.45 |
| 755.80 | 3.60 | 3.60 |
| 783.85 | 3.95 | 3.95 |
| 525.56 | 1.42 | 1.42 |
| 525.56 | 1.42 | 1.42 |
| 503.58 | 1.12 | 1.12 |
| 559.69 | 2.68 | 2.68 |
| 559.69 | 2.67 | 2.67 |
| 539.59 | 1.81 | 1.81 |
| 539.59 | 1.81 | 1.81 |
| 587.74 | 3.46 | 3.46 |
| 699.95 | 6.58 | 6.58 |
| 924.39 | 12.82 | 12.82 |
| 639.57 | 2.98 | 2.98 |
| 579.53 | 1.96 | 1.96 |
| 579.53 | 1.96 | 1.96 |
| 984.23 | 9.37 | 9.37 |
| 573.67 | 2.47 | 2.47 |
| 587.70 | 2.86 | 2.86 |
| 630.76 | 2.43 | 2.43 |
| 643.72 | 2.66 | 2.66 |
| 529.62 | 1.65 | 1.65 |
| 527.60 | 1.43 | 1.43 |
| 585.59 | 1.12 | 1.12 |
| 683.69 | 2.33 | 2.33 |
| 683.69 | 2.33 | 2.33 |
| 741.68 | 2.02 | 2.02 |
| 517.56 | 0.80 | 0.80 |
| 559.60 | 1.37 | 1.37 |
| 687.72 | 2.80 | 2.80 |
| 515.52 | 0.94 | 0.94 |