Basic Information
ID: ALA3388960
Type: Functional
Description: Reduction in ADAMTS-4/ADAMTS-5-mediated aggrecan cleavage products in po dosed Lewis rat MIA model assessed as aggrecanase-cleaved fragments treatment starting from day 3 and single dose given on day 7 followed by animal sacrificed 4 hrs later by NITEGE sandwich ELISA assay
Organism: Rattus norvegicus
Strain: Lewis
Activity Charts
Bioactivity
Activity Types for Assay ALA3388960
ED50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 387.78 | 1.28 | 1.28 |
| 421.34 | 1.65 | 1.65 |