Basic Information
ID: ALA3389020
Type: Binding
Description: Inhibition of EGFR L858R/T970M double mutant phosphorylation in human NCI-H1975 cells after 2 hrs by fluorescence assay
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA3389020
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 519.01 | 4.07 | 4.07 |
| 483.58 | 4.25 | 4.25 |
| 477.96 | 4.25 | 4.25 |
| 590.09 | 3.53 | 3.53 |
| 576.06 | 3.32 | 3.32 |
| 616.13 | 4.11 | 4.11 |
| 616.13 | 4.11 | 4.11 |
| 576.06 | 3.19 | 3.19 |
| 577.05 | 3.35 | 3.35 |
| 617.11 | 3.47 | 3.47 |
| 576.06 | 3.32 | 3.32 |
| 533.04 | 4.46 | 4.46 |
| 521.03 | 4.32 | 4.32 |
| 519.01 | 4.07 | 4.07 |
| 524.63 | 4.38 | 4.38 |
| 534.06 | 5.16 | 5.16 |
| 520.04 | 5.15 | 5.15 |
| 513.65 | 4.82 | 4.82 |
| 499.62 | 4.51 | 4.51 |
| 485.59 | 4.50 | 4.50 |
| 485.59 | 4.17 | 4.17 |