Basic Information
ID: ALA3389506
Type: Binding
Description: Antagonist activity against rat TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3389506
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 154.25 | 2.67 | 2.67 |
| 156.27 | 2.75 | 2.75 |
| 154.25 | 2.67 | 2.67 |
| 196.29 | 3.24 | 3.24 |
| 198.31 | 3.32 | 3.32 |
| 196.29 | 3.24 | 3.24 |
| 272.39 | 4.84 | 4.84 |
| 272.39 | 4.84 | 4.84 |
| 283.37 | 4.41 | 4.41 |
| 394.36 | 6.57 | 6.57 |
| 286.42 | 4.77 | 4.77 |
| 306.83 | 5.12 | 5.12 |
| 302.41 | 4.47 | 4.47 |
| 286.42 | 4.86 | 4.86 |
| 305.85 | 4.69 | 4.69 |
| 285.43 | 4.43 | 4.43 |
| 306.84 | 5.15 | 5.15 |
| 278.44 | 4.31 | 4.31 |
| 329.48 | 5.77 | 5.77 |
| 328.50 | 5.80 | 5.80 |
| 272.39 | 4.84 | 4.84 |
| 272.39 | 4.84 | 4.84 |
| 283.37 | 4.41 | 4.41 |
| 286.42 | 4.77 | 4.77 |
| 306.83 | 5.12 | 5.12 |
| 302.41 | 4.47 | 4.47 |
| 398.28 | 5.07 | 5.07 |
| 322.45 | 5.62 | 5.62 |
| 286.42 | 4.86 | 4.86 |
| 305.85 | 4.69 | 4.69 |
| 285.43 | 4.43 | 4.43 |
| 306.84 | 5.15 | 5.15 |
| 278.44 | 4.31 | 4.31 |
| 329.48 | 5.77 | 5.77 |
| 329.48 | 6.23 | 6.23 |
| 274.40 | 4.92 | 4.92 |
| 288.43 | 4.85 | 4.85 |
| 308.85 | 5.20 | 5.20 |
| 288.43 | 4.94 | 4.94 |