Basic Information
ID: ALA3389592
Type: Binding
Description: Inhibition of N-terminal His6-tagged mouse DNMT1 (731 to 1602 residues) expressed in Escherichia coli BL21 (DE3) incubated for 15 mins before addition of [3H]-SAM and poly(dI-dC).poly(dI-dC) by liquid scintillation counting based radioactive methylation assay
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA3389592
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 322.45 | 3.89 | 3.89 |
| 334.46 | 3.67 | 3.67 |
| 383.50 | 4.47 | 4.47 |
| 383.50 | 4.47 | 4.47 |
| 383.50 | 4.47 | 4.47 |
| 452.39 | 5.78 | 5.78 |
| 344.46 | 3.99 | 3.99 |
| 298.39 | 2.39 | 2.39 |
| 442.15 | 3.26 | 3.26 |
| 297.40 | 3.56 | 3.56 |
| 505.66 | 6.35 | 6.35 |
| 505.66 | 6.35 | 6.35 |
| 505.66 | 6.35 | 6.35 |