Basic Information
ID: ALA3389954
Type: Functional
Description: Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated for 30 mins before LTD4 addition by Fura2-AM assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3389954
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 472.65 | 6.66 | 6.66 |
| 595.73 | 6.28 | 6.28 |
| 589.69 | 6.01 | 6.01 |
| 510.55 | 5.10 | 5.10 |
| 446.50 | 4.60 | 4.60 |
| 446.50 | 4.60 | 4.60 |
| 446.50 | 4.60 | 4.60 |
| 488.54 | 4.54 | 4.54 |
| 502.57 | 4.93 | 4.93 |
| 516.59 | 5.32 | 5.32 |
| 546.58 | 4.38 | 4.38 |
| 560.60 | 4.77 | 4.77 |
| 574.63 | 5.16 | 5.16 |
| 532.59 | 4.86 | 4.86 |
| 546.62 | 5.25 | 5.25 |
| 560.65 | 5.64 | 5.64 |
| 518.57 | 4.47 | 4.47 |
| 546.62 | 5.25 | 5.25 |
| 520.54 | 3.91 | 3.91 |
| 534.57 | 4.30 | 4.30 |
| 548.59 | 4.69 | 4.69 |
| 532.59 | 4.86 | 4.86 |
| 532.59 | 4.86 | 4.86 |