Basic Information
ID: ALA3389993
Type: Binding
Description: Inhibition of purified recombinant Escherichia coli topoisomerase 1 assessed as relaxation of supercoiled plasmid DNA after 30 mins by electrophoretic analysis
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA3389993
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 346.47 | 5.40 | 5.40 |
| 430.50 | 5.19 | 5.19 |
| 322.45 | 5.07 | 5.07 |
| 278.35 | 3.79 | 3.79 |
| 340.42 | 5.06 | 5.06 |
| 368.47 | 5.84 | 5.84 |
| 284.36 | 3.83 | 3.83 |
| 296.32 | 3.56 | 3.56 |
| 340.42 | 4.95 | 4.95 |
| 323.39 | 3.98 | 3.98 |