Basic Information
ID: ALA3389998
Type: Binding
Description: Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in enzyme-catalyzed supercoiling of relaxed circular pBR322 DNA by agarose gel electrophoresis
Format: BAO_0000223
Organism: Staphylococcus aureus
Target: DNA gyrase(ALA3038482)
Document: ALA3351553
Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in enzyme-catalyzed supercoiling of relaxed circular pBR322 DNA by agarose gel electrophoresis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3389998
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 331.35 | 1.58 | 1.58 |
| 471.69 | 6.45 | 6.45 |
| 501.67 | 5.51 | 5.51 |
| 471.69 | 6.45 | 6.45 |
| 471.69 | 6.45 | 6.45 |
| 469.67 | 6.60 | 6.60 |
| 457.66 | 6.27 | 6.27 |
| 429.60 | 5.46 | 5.46 |
| 415.58 | 5.15 | 5.15 |
| 433.57 | 5.29 | 5.29 |
| 450.02 | 5.80 | 5.80 |
| 494.47 | 5.91 | 5.91 |
| 445.60 | 5.16 | 5.16 |
| 475.58 | 4.78 | 4.78 |
| 485.71 | 6.84 | 6.84 |
| 457.66 | 6.06 | 6.06 |
| 443.63 | 5.67 | 5.67 |
| 459.59 | 4.85 | 4.85 |
| 491.68 | 6.82 | 6.82 |
| 515.69 | 5.60 | 5.60 |
| 455.69 | 6.95 | 6.95 |
| 441.66 | 6.56 | 6.56 |
| 427.63 | 6.17 | 6.17 |
| 413.61 | 6.13 | 6.13 |
| 456.67 | 6.43 | 6.43 |
| 457.66 | 6.40 | 6.40 |
| 470.70 | 6.41 | 6.41 |
| 455.64 | 6.21 | 6.21 |
| 441.62 | 5.81 | 5.81 |
| 427.59 | 5.77 | 5.77 |
| 427.63 | 6.17 | 6.17 |
| 389.51 | 5.02 | 5.02 |
| 405.97 | 5.53 | 5.53 |
| 450.42 | 5.64 | 5.64 |
| 439.52 | 5.90 | 5.90 |
| 401.55 | 4.89 | 4.89 |
| 428.62 | 5.57 | 5.57 |
| 416.52 | 4.79 | 4.79 |
| 386.54 | 4.46 | 4.46 |
| 414.59 | 4.94 | 4.94 |
| 447.62 | 6.54 | 6.54 |
| 448.61 | 5.94 | 5.94 |
| 448.61 | 5.94 | 5.94 |
| 441.62 | 5.17 | 5.17 |
| 433.60 | 6.50 | 6.50 |
| 395.59 | 5.24 | 5.24 |
| 379.59 | 5.75 | 5.75 |
| 477.65 | 6.77 | 6.77 |