Basic Information
ID: ALA3390425
Type: Binding
Description: Antagonist activity at alpha1B adrenoceptor in Wistar rat spleen assessed as phenylephrine-induced contractions after 30 mins
Format: BAO_0000357
Organism: Rattus norvegicus
Strain: Wistar
Tissue: Spleen
Target: Alpha-1b adrenergic receptor(ALA315)
Document: ALA3351355
Antagonist activity at alpha1B adrenoceptor in Wistar rat spleen assessed as phenylephrine-induced contractions after 30 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3390425
pKb
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 346.47 | 2.89 | 2.89 |
| 364.51 | 2.46 | 2.46 |
| 348.44 | 1.74 | 1.74 |
| 437.58 | 3.22 | 3.22 |
| 380.51 | 1.47 | 1.47 |
| 396.51 | 1.14 | 1.14 |
| 347.46 | 1.31 | 1.31 |
| 423.56 | 3.23 | 3.23 |
| 424.55 | 2.62 | 2.62 |
| 451.57 | 2.87 | 2.87 |
| 519.56 | 3.88 | 3.88 |
| 441.53 | 2.46 | 2.46 |
| 457.62 | 3.13 | 3.13 |
| 444.58 | 1.30 | 1.30 |
| 389.50 | 1.57 | 1.57 |
| 443.47 | 2.11 | 2.11 |
| 487.62 | 2.41 | 2.41 |
| 501.65 | 2.72 | 2.72 |
| 522.07 | 3.07 | 3.07 |
| 571.62 | 3.31 | 3.31 |
| 532.62 | 2.32 | 2.32 |
| 532.62 | 2.32 | 2.32 |
| 493.65 | 2.48 | 2.48 |
| 425.55 | 0.98 | 0.98 |
| 466.58 | 3.26 | 3.26 |
| 446.59 | 2.53 | 2.53 |
| 446.59 | 2.53 | 2.53 |