ID: ALA3390701
Type: Binding
Description: Antagonist activity at PAR4 in PAR-4-AP-stimulated human platelets assessed as PAC1 binding at 10 uM pretreated for 5 mins by fluorescent PAC1 integrin alpha2bb3 activation assay relative to control
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA3390701
%max
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
268.32 | 2.74 | 2.74 |
344.41 | 4.25 | 4.25 |
362.40 | 4.39 | 4.39 |
412.41 | 5.27 | 5.27 |
374.44 | 4.26 | 4.26 |
378.86 | 4.91 | 4.91 |
428.41 | 5.15 | 5.15 |
346.41 | 2.14 | 2.14 |
452.53 | 3.66 | 3.66 |
456.95 | 4.31 | 4.31 |
440.50 | 3.80 | 3.80 |
490.50 | 4.67 | 4.67 |
506.50 | 4.55 | 4.55 |
293.33 | 2.61 | 2.61 |
369.42 | 4.12 | 4.12 |
399.45 | 4.13 | 4.13 |
403.87 | 4.78 | 4.78 |
437.42 | 5.14 | 5.14 |
453.42 | 5.02 | 5.02 |
312.33 | 2.47 | 2.47 |
406.41 | 4.12 | 4.12 |
456.42 | 5.00 | 5.00 |
388.42 | 3.98 | 3.98 |
422.87 | 4.63 | 4.63 |
424.40 | 4.26 | 4.26 |
269.30 | 2.14 | 2.14 |
345.40 | 3.65 | 3.65 |
429.40 | 4.55 | 4.55 |
413.40 | 4.67 | 4.67 |
375.43 | 3.66 | 3.66 |
424.30 | 4.41 | 4.41 |
379.85 | 4.30 | 4.30 |
363.39 | 3.79 | 3.79 |