Basic Information
ID: ALA3390766
Type: Functional
Description: Antipyroptotic activity in PMA-differentiated and LPS-primed human THP1 cells assessed as decrease in ATP-induced pyroptosis measured as LDH activity at 10 uM after 1 hrs by colorimetric assay
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA3390766
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 159.19 | 1.80 | 1.80 |
| 204.19 | 1.71 | 1.71 |
| 160.18 | 1.19 | 1.19 |
| 248.32 | 2.76 | 2.76 |
| 240.69 | 2.49 | 2.49 |
| 236.27 | 1.85 | 1.85 |
| 193.63 | 2.45 | 2.45 |
| 240.69 | 2.49 | 2.49 |
| 228.08 | 3.11 | 3.11 |
| 275.13 | 3.15 | 3.15 |
| 207.23 | 1.23 | 1.23 |
| 251.24 | 1.75 | 1.75 |
| 224.23 | 1.98 | 1.98 |
| 285.14 | 2.60 | 2.60 |
| 206.24 | 1.84 | 1.84 |
| 240.69 | 2.49 | 2.49 |
| 275.13 | 3.15 | 3.15 |
| 275.13 | 3.15 | 3.15 |
| 220.27 | 2.15 | 2.15 |
| 144.17 | 0.49 | 0.49 |
| 212.29 | 2.05 | 2.05 |
| 177.18 | 1.94 | 1.94 |
| 238.08 | 2.56 | 2.56 |
| 209.25 | 2.95 | 2.95 |
| 228.08 | 3.11 | 3.11 |
| 340.80 | 3.47 | 3.47 |
| 375.25 | 4.12 | 4.12 |
| 375.25 | 4.12 | 4.12 |
| 224.69 | 2.91 | 2.91 |
| 212.63 | 2.01 | 2.01 |
| 253.73 | 2.46 | 2.46 |
| 366.58 | 3.26 | 3.26 |
| 366.58 | 3.26 | 3.26 |
| 316.78 | 4.02 | 4.02 |
| 316.78 | 4.02 | 4.02 |
| 254.71 | 2.88 | 2.88 |
| 254.71 | 2.88 | 2.88 |
| 242.70 | 2.57 | 2.57 |