Inhibition of DOT1L in human MV4-11 cells assessed as downregulation of HOXA9/MEIS1 mRNA expression after 6 days by real-time PCR analysis

Basic Information

ID: ALA3390904

Type: Binding

Description: Inhibition of DOT1L in human MV4-11 cells assessed as downregulation of HOXA9/MEIS1 mRNA expression after 6 days by real-time PCR analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: MV4-11

Target: Histone-lysine N-methyltransferase, H3 lysine-79 specific(ALA1795117)

Document: ALA3390834

Inhibition of DOT1L in human MV4-11 cells assessed as downregulation of HOXA9/MEIS1 mRNA expression after 6 days by real-time PCR analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3390904

IC50

Total(1)

Parent Molecular Weight	ALogP	Polar Surface Area
539.68	2.85	2.85

Parent Molecular Weight

ALogP

Polar Surface Area

539.68

2.85

Inhibition of DOT1L in human MV4-11 cells assessed as downregulation of HOXA9/MEIS1 mRNA expression after 6 days by real-time PCR analysis

Basic Information

Activity Charts

Compound Summary