Basic Information
ID: ALA3391333
Type: Binding
Description: Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of lithium dodecyl sulphate-stimulated ROS generation preincubated for 15 mins followed by lithium dodecyl sulphate challenge by cell-free assay in presence of NADPH
Format: BAO_0000219
Organism: Homo sapiens
Cell type: COS 22
Target: Cytochrome b-245 heavy chain(ALA1287627)
Document: ALA3390837
Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of lithium dodecyl sulphate-stimulated ROS generation preincubated for 15 mins followed by lithium dodecyl sulphate challenge by cell-free assay in presence of NADPH: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3391333
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 390.41 | 6.84 | 6.84 |
| 416.43 | 6.92 | 6.92 |