Basic Information
ID: ALA3395114
Type: Binding
Description: Inhibition of BACE1 in HEK293T cells expressing APPswedish mutant assessed as inhibition of amyloid beta 40 production by sandwich ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK-293T
Target: Beta-secretase 1(ALA4822)
Document: ALA3393054
Inhibition of BACE1 in HEK293T cells expressing APPswedish mutant assessed as inhibition of amyloid beta 40 production by sandwich ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3395114
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 447.44 | 4.52 | 4.52 |
| 430.44 | 3.78 | 3.78 |
| 458.49 | 4.56 | 4.56 |
| 430.44 | 3.78 | 3.78 |
| 432.46 | 3.87 | 3.87 |
| 432.46 | 3.87 | 3.87 |
| 432.46 | 4.22 | 4.22 |
| 432.46 | 4.22 | 4.22 |
| 433.44 | 2.81 | 2.81 |
| 461.50 | 3.59 | 3.59 |
| 467.45 | 4.21 | 4.21 |
| 453.42 | 3.82 | 3.82 |
| 435.43 | 3.53 | 3.53 |
| 435.43 | 3.53 | 3.53 |
| 424.44 | 4.64 | 4.64 |
| 425.42 | 4.04 | 4.04 |
| 425.42 | 4.04 | 4.04 |
| 425.42 | 4.04 | 4.04 |
| 439.45 | 4.35 | 4.35 |
| 443.41 | 4.18 | 4.18 |
| 429.45 | 4.39 | 4.39 |